产品货号：
Z31399
中文名称：
Cystatin B/CSTB抗体
英文名称：
Anti-Cystatin B/CSTB Antibody (Clone#2B6)
产品规格：
50μl|100μl|150μl
发货周期：
1～3天
产品价格：
询价
| 抗体名称 | Anti-Cystatin B/CSTB Antibody (Clone#2B6) |
| 指标别名 | CPI B;CST6;CSTB;Cystatin B;cystatin B (stefin B);EPM1;PME;Stefin B;STFB |
| 克隆性 | Monoclonal |
| 检验物种 | human |
| 应用范围 | WB,IHC,IHC-F,ICC,FCM |
| 基因名称 | CSTB |
| 克隆号 | 2B6 |
| 抗体来源 | Mouse |
| 抗体类型 | IgG1 |
| 免疫原 | E.coli-derived human Stefin B recombinant protein (Position:M1-F98).Human Stefin B shares 78.6% amino acid (aa) sequence identity with both mouse and rat Stefin B. |
| 实际分子量 | 14KD |
| 成分 | 500μg/mL antibody with PBS，0.02% NaN3,1mg BSA and 50% glycerol. |
| 纯化方式 | protein G purified. |
| 浓度 | 500μg/mL |
| 产品形态 | 溶液 |
| 保存条件 | 12 months from date of receipt，-20℃ as supplied.6 months 2 to 8℃ after reconstitution.Avoid repeated freezing and thawing. |
| 背景资料 | Cystatin B (CSTB),also called STFB,is a small protein that is a member of the superfamily of cysteine protease inhibitors.It has been isolated from human spleen and liver and its amino acid sequence has been fully determined.The cystatin B gene is located on 21q22.3.It is widely distributed and is localized mostly intracellularly,but has been found extracellularly.The protein is able to form a dimer stabilized by noncovalent forces,inhibiting papain and cathepsins l,h and b.Its role is thought to be as a protector against the proteinases leaking from lysosomes.A cystatin B multiprotein complex might have a specific cerebellar function,and that the loss of this function might contribute to the etiopathogenesis of EPM1.Upon differentiation to myotubes,CSTB becomes excluded from the nucleus and lysosomes,suggesting that the subcellular distribution of CSTB is dependent on the differentiation status of the cell. |
| Uniprot ID | P04080 |
| 推荐配套试剂 | Biorab recommends Enhanced Chemiluminescent Kit with anti-Mouse IgG (ZN1928) for Western blot,and HRP Conjugated anti-Mouse IgG Super Vision Assay Kit (ZN1866) for IHC(P) and ICC. |
| 推荐稀释比 | Western blot(WB) 1:500～2000 Immunohistochemistry in paraffin section (IHC) 1:50～400 Immunohistochemistry in frozen section 1:50～400 Immunocytochemistry in fixed cells 1:50～400 Flow cytometry (FCM) 1～3μg/1×106 cells (Boiling the paraffin sections in 10mM citrate buffer,pH6.0,or PH8.0 EDTA repair liquid for 20 mins is required for the staining of formalin/paraffin sections.) Optimal working dilutions must be determined by end user. |
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